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. 2017 Jun 28;89(15):7966–7973. doi: 10.1021/acs.analchem.7b01161

Table 1. Descriptive Results of the HDX-MS Analysis of Hemoglobin and IgG4Δhinge with An-PEP or Pepsin.

Hemoglobin
  unique peptides
sequence coverage
redundancy
  α subunit β subunit total α subunit β subunit total α subunit β subunit
An-PEP 30 8 38 99 92 96 4 1.7
pepsin 13 14 27 89 99 95 2.8 2.6
IgG4Δhinge
  unique peptides
sequence coverage
redundancy
  light chain heavy chain total light chain heavy chain total light chain heavy chain
An-PEP 19 69 88 88 92 91 2.1 3.5
pepsin 24 75 99 100 90 93 3.2 4.3