Figure 7.

Reduced ${\chi }_{\text{free}}^2$ goodness-of-fit of identified ensembles vs sampling time for aMD (blue) and cMD (green) simulations of (a) non-native K63, (b) native K63, (c) non-native K48, and (d) native K48 linkages. Remaining systems can be found in Figure S11. In the systems presented above, the aMD simulations are the quickest to escape poor initial models, as shown by the more rapid initial decrease in ${\chi }_{\text{free}}^2$ in comparison to the cMD models.