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. Author manuscript; available in PMC: 2017 Aug 3.
Published in final edited form as: Nano Lett. 2016 Aug 8;16(9):5401–5408. doi: 10.1021/acs.nanolett.6b01632

Figure 1.

Figure 1

(A) Synthesis of conjugates. (i) PTX, DCC, DMAP, r.t.; (ii) acetic anhydride; (iii) pTsOH, reflux; (iv) EDCI, HOBt, DMAP, r.t.; (v) EDCI, HOBt, r.t. (B) Schematic representation of the preparation of PEGylated prodrug NPs of PTX-S-OA.