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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Mod Pathol. 2016 Jul 22;29(11):1381–1389. doi: 10.1038/modpathol.2016.135

Table 3.

Important clinical and pathological characteristics in endometrial cancer patients according to germline mutation status.

Characteristic No DM N(%) LS DM N(%) Other DM N(%) p-value No DM vs LS p-value No DM vs Other

Age at Diagnosis, mean (SD) 62 (10.7) 52 (9.1) 58 (14.7) p<0.01 p=0.21

Age at Diagnosis <50 p<0.01 p=0.62
 Yes 38 (11) 10 (46) 2 (15)
 No 308 (89) 12 (55) 11 (85)

BMI p=0.01 P=0.39
 Not Overweight 50 (15) 8 (36) 3 (23)
 Overweight 296 (86) 14 (64) 10 (77)

Tumor Location p<0.01 p=0.98
 Corpus 310 (93) 14 (70) 12 (92)
 Lower Uterine Segment 25 (8) 6 (30) 1 (8)

MSI or IHC Screen Positive p<0.01 p=0.91
 Yes 31 (9) 19 (91) 1 (8)
 No 301 (91) 2 (10) 11 (92)

SGO 5–10% Criteria p<0.01 p=0.59
 Yes 84 (24) 13 (59) 4 (31)
 No 262 (76) 9 (41) 9 (69)

Serous Histology p=0.73 p=0.02
 Serous 22 (6) 1 (5) 3 (23)
 Other 324 (94) 21 (96) 10 (77)