Table 6.
Clinical characteristics by type of LS mutation.
| Clinical Characteristic |
MLH1 (N=3) N (%) |
MSH2 (N=5) N (%) |
EPCAM-MSH2 (N=2) N (%) |
MSH6 (N=6) N (%) |
PMS2 (N=6) N (%) |
|---|---|---|---|---|---|
|
| |||||
| Age at Diagnosis <50 | |||||
| Yes | 3 (100) | 4 (80) | 1 (50) | 1 (17) | 1 (17) |
| No | 0 (0) | 1 (20) | 1 (50) | 5 (83) | 5 (83) |
|
| |||||
| SGO 5–10% Criteria | |||||
| Yes | 3 (100) | 4 (80) | 2 (100) | 3 (50) | 1 (17) |
| No | 0 (0) | 1 (20) | 0 (0) | 3 (50) | 5 (83) |
|
| |||||
| FDR1 or SDR2 with LS associated CA | |||||
| Yes | 3 (100) | 4 (80) | 2 (100) | 1 (17) | 3 (50) |
| No | 0 (0) | 1 (20) | 0 (0) | 5 (83) | 3 (50) |
1
FDR = first degree relative,
2
SDR = second degree relative