Table 3.
Multivariate Cox regression analysis for LC and LWR in cohort 1(N = 378)
| Prognostic factors | Median survival time (95% CI) | HRa(95% CI) | P value |
|---|---|---|---|
| LC | 0.912 | ||
| Quartile 1(<0.8 × 10*9/L) | 40.0 (32.1 ~ 48.0) | Reference | - |
| Quartile 2(~1.1 × 10*9/L) | 45.0 (28.2 ~ 61.8) | 1.135(0.805 ~ 1.600) | 0.471 |
| Quartile 3(~1.5 × 10*9/L) | 58.0 (31.8 ~ 84.2) | 1.081(0.768 ~ 1.520) | 0.655 |
| Quartile 4(≥1.5 × 10*9/L) | 60.0 (40.5 ~ 79.5) | 1.082(0.777 ~ 1.506) | 0.642 |
| LWR | |||
| Quartile 1(<0.086) | 19.0(13.0 ~ 25.0) | Reference | - |
| Quartile 2(~0.138) | 47.0(30.8 ~ 63.2) | 0.563(0.407 ~ 0.778) | 0.001 |
| Quartile 3(~0.208) | 79.0(40.3 ~ 117.7) | 0.532(0.381 ~ 0.742) | <0.001 |
| Quartile 4(≥0.208) | 101.0(55.1 ~ 146.9) | 0.466(0.328 ~ 0.661) | <0.001 |
LC lymphocyte count, LWR lymphocyte to white blood cell ratio, OS overall survival, HR hazard ratio, CI confidence interval
aCox regression model controlling for Age; Gender; Family history; Smoke history; Nutrient status; ECOG; Primary tumor site; Tumor stage; Concomitant disease