Table 1.

The comparison results of different methods obtained under the 10-fold cross validation on GDSC dataset

Methods	Drug-averaged PCC_S/R	Drug-averaged RMSE_S/R	Drug-averaged RMSE_S/R	Drug-averaged RMSE
SRMF (drug response + gene expression)	0.71 (±0.15)	1.73 (±0.46)	0.62 (±0.16)	1.43 (±0.36)
SRMF (drug response)	0.69 (±0.16)	1.72 (±0.48)	0.59 (±0.17)	1.45 (±0.39)
KBMF	0.59 (±0.14)	2.00 (±0.51)	0.49 (±0.14)	1.59 (±0.42)
DLN	0.55 (±0.14)	2.49 (±0.85)	0.44 (±0.13)	2.08 (±0.83)
RF	0.50 (±0.15)	2.23 (±0.66)	0.40 (±0.14)	1.69 (±0.50)

PCC_S/R—Drug-averaged Pearson correlation for responses from sensitive and resistant cell lines; RMSE_S/R—Drug-averaged root-mean-square error for responses from sensitive and resistant cell lines; PCC—Drug-averaged Pearson correlation for responses across all cell lines; RMSE—Drug-averaged root-mean-square error for responses across all cell lines. The value shown in the bracket represents standard deviation