Table 2.

HRs for shift work exposure groups applying multiple Cox analysis for prediction of prostate cancer (no cancer as reference) after baseline among male night workers and with 95% CI. Reference: non-exposed. n=12 322, total number of cases=454

	Duration of exposure, years	Cases/no cases	Complete follow-up HR (95% CI)*	Follow-up to 60 years HR (95% CI)†
No night work versus ever night work
No night work (ref) Working nights for: (unadjusted)	0 1–45 years	294/7212 160/4656	1 0.84 (0.69 to 1.03)	1 0.78 (0.64 to 0.96)
No night work (ref) Working nights for: (adjusted)‡	0 1–45 years	294/7212 160/4656	1 0.91 (0.74 to 1.12)	1 0.89 (0.72 to 1.09)
No night work versus years of shift work
No night work (ref) Working nights for: (unadjusted)	0 years 1–5 years 6–10 years 11–20 years 21–45 years	294/7212 55/1729 31/800 38/968 36/1159	1 0.79 (0.60 to 1.06) 0.99 (0.68 to 1.43) 1.00 (0.72 to 1.41) 0.77 (0.55 to 1.09)	1 0.72 (0.54 to 0.96) 0.88 (0.61 to 1.27) 0.84 (0.60 to 1.18) 0.86 (0.61 to 1.21)
No night work (ref) Working nights for: (adjusted)‡	0 years 1–5 years 6–10 years 11–20 years 21–45 years	294/7212 55/1729 31/800 38/968 36/1159	1 0.86 (0.63 to 1.17) 1.09 (0.74 to 1.61) 1.12 (0.78 to 1.63) 0.72 (0.50 to 1.05)	1 0.84 (0.62 to 1.15) 0.96 (0.65 to 1.42) 1.11 (0.77 to 1.60) 0.75 (0.52 to 1.09)

*Follow-up until 31 December 2010.

†Follow-up until the age of 60.

‡Adjusted for: age + education level + tobacco consumption + BMI + having children + coffee consumption + previous cancer.

BMI, body mass index.