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. 2017 Jul 5;4(7):170362. doi: 10.1098/rsos.170362

Figure 4.

Figure 4.

CYP27C1 is specifically expressed in the RPE of adult upstream migrant lamprey. (a) ISH of cross sections of retina and RPE from juvenile and adult lamprey. The CYP27C1 antisense probe labels the CYP27C1 transcript in the RPE of adults; only weak background signal was observed in the negative control (CYP27C1 sense probe), and the Rhodopsin (RHO) antisense probe (positive control) labels RHO in the ONL of both adults and juveniles. RPE, retinal pigment epithelium; ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer; H&E, haematoxylin and eosin staining. (b) qPCR analyses indicate that CYP27C1 transcript levels are significantly higher in the RPE of adult lamprey compared with juveniles.