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. 2017 Jul 3;6(7):e354. doi: 10.1038/oncsis.2017.56

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Copyright © 2017 The Author(s)

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Evaluation of tumors generated following xenografting of either non-irradiated, P or X irradiated CAL33 cells in immunodeficient mice. (a) Average tumor volume (mm³); (b) Representative images of tumor xenografts; (c) Heatmap of 10 most up- and downregulated mouse genes in tumors generated by non-irradiated cells versus P or X tumors, and in P versus X tumors; (d) Heatmap of 10 most up- and downregulated human genes in tumors generated by non-irradiated cells versus P or X tumors, and in P versus X tumors; (e) Venn diagrams showing common upregulated and downregulated human genes between P and X tumors. Framed genes are commonly expressed in P and X tumors. Selection is adjusted P-value<0.05 and lofFC>1.