Table 2. Common upregulated and downregulated human genes in tumors generated with either X or P irradiated cells.

Common up-regulated genes between X versus 0 and P versus 0
Role	Gene abbreviation	Gene full name
Metastasis/Angiogenesis
	KRT16	Keratin 16
	SERPINB3	Serpin family B member 3
	CAPNS2	Calpain small subunit 2
	GRHL3	Grainyhead like transcription factor 3
	CSTB	Cystatin B
	PRSS27	Protease, serine 27
	TLE4	Transducin like enhancer of split 4
	TMPRSS11D	Transmembrane protease, serine 11D
Inflammation	PGLYRP3	Peptidoglycan recognition protein 3
	RASGRP1	RAS guanyl releasing protein 1
	ENDOU	Endonuclease, poly(U) specific
	METRNL	Meteorin like, glial cell differentiation regulator
	S100A8	S100 calcium binding protein A8
	S100A9	S100 calcium binding protein A9
	A2ML1	Alpha-2-macroglobulin like 1
	HCN2	Hyperpolarization activated cyclic nucleotide gated potassium channel 2
	CHST2	Carbohydrate sulfotransferase 2
M1/M2	ABCG1	ATP binding cassette subfamily G member 1
Proliferation	HPGD	Hydroxyprostaglandin dehydrogenase 15-(NAD)
	BNIPL	BCL2 interacting protein like
	PPP2R2C	Protein phosphatase 2 regulatory subunit Bgamma
	KLK8	Kallikrein related peptidase 8
	GJB6	Gap junction protein beta 6
	EEF1A2	Eukaryotic translation elongation factor 1 alpha 2
	EPHA4	EPH receptor A4
	GAS7	Growth arrest specific 7
	DSG1	Desmoglein 1
	PDZK1IP1	PDZK1 interacting protein 1
	TMPRSS11A	Transmembrane protease, serine 11A
	FLRT2	Fibronectin leucine rich transmembrane protein 2
Other	C12orf36	Putative uncharacterized protein C12orf36
	FRMPD1	FERM and PDZ domain containing 1
	TMEM45A	Transmembrane protein 45A
	LIPK	Lipase family member K
	CTC-490G23.2	CTC-490G23.2
	HOPX	HOP homeobox
	PLIN2	Perilipin 2
	SDR9C7	Short chain dehydrogenase/reductase family 9C, member 7
	STXBP5-AS1	STXBP5 antisense RNA 1
	ARRDC4	Arrestin domain containing 4
	FRY	FRY microtubule binding protein
	FAM25A	Family with sequence similarity 25 member A [
	SCEL	Sciellin
	GJB2	Gap junction protein beta 2
	UNC5B-AS1	UNC5B antisense RNA 1
	RP11-21B23.2	Pre-mRNA processing factor
	SPRR1B	Small proline rich protein 1B
	NAV3	Neuron navigator 3
	SLC10A6	Solute carrier family 10 member 6
	RP11-275I14.4	Pre-mRNA processing factor
	RP11-356I2.4	Pre-mRNA processing factor
	C9orf169	Cysteine rich tail 1
	RP11-321G12.1	Pre-mRNA processing factor
	LINC01094	Long intergenic non-protein coding RNA 1094
	OR7E62P	Olfactory receptor family 7 subfamily E member 62 pseudogene
	FAM3D	Family with sequence similarity 3 member D
	SMIM5	Small integral membrane protein 5
	FBXL16	F-box and leucine rich repeat protein 16
	RP11-783K16.5	Pre-mRNA processing factor
	KCNK7	Potassium two pore domain channel subfamily K member 7
	FAM25HP	Family with sequence similarity 25, member H pseudogene
	WI2-85898F10.1	Uncharacterized LOC107985535
	IVL	Involucrin
	TCN1	Transcobalamin 1
	KLHL4	Kelch like family member 4
	LRRC7	Leucine rich repeat containing 7
	RP11-557H15.3	Pre-mRNA processing factor
	TSHZ2	Teashirt zinc finger homeobox 2
	OLFM2	Olfactomedin 2
	ADH7	Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Common down-regulated genes between X versus 0 and P versus 0
Role	Gene abbreviation	Gene full name
Proliferation	LIF	leukemia inhibitory factor
Other	RNA5-8SP2	RNA, 5.8S ribosomal pseudogene 2
	P2RX5	purinergic receptor P2X 5

In bold are shown genes upregulated in either P or X tumors, but down-regulated in tumors generated with non-irradiated cells. Selection is adjusted P-value<0.05 and lofFC>1.