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. 2017 Jul 10;6(7):e358. doi: 10.1038/oncsis.2017.58

Figure 7.

Figure 7

miR-200b inactivates PI3K/Akt signaling pathway through FUT4 downregulation. (a, b) Phosphorylation of PI3K, PDK and Akt was analyzed by western blotting and statistical analysis. Cells were transfected with miR-200b mimics and co-transfected with FUT4 cDNA or FUT4 cDNA alone, respectively. (c, d) Phosphorylation of PI3K, PDK and Akt was analyzed by western blotting and statistical analysis. Cells were transfected with Anti-miR-200b and co-transfected with FUT4 siRNA or FUT4 siRNA alone, respectively. *P<0.05, **P<0.01, ***P<0.001.