Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 31;6(7):e368. doi: 10.1038/oncsis.2017.60

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 The Author(s)

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

MeCP2 facilitates the expression of GIT1 in GC cells. (a) GIT1 mRNA expression in GC tissues versus normal tissues. *P<0.01. (b) MeCP2 and GIT1 expressions showed a positive correlation. The 2^−ΔΔCt values of MeCP2 and GIT1 mRNA were subjected to a Pearson correlation analysis (n=76, r=0.869, P<0.0001). (c) Protein levels of GIT1 in tumor tissues and normal tissues were measured by immunohistochemical staining. (d) Protein expression levels of GIT1 and MeCP2 were measured by western blotting. (e) MeCP2 and GIT1 protein expressions showed a positive correlation (n=76, r=0.763, P<0.0001). (f) GIT1 mRNA expression in BGC-823 cells transfected with MeCP2 shRNA or MeCP2 overexpression vector. *P<0.01 compared with Ctrl, ^#P<0.01 compared with sh-Ctrl, n=3. (g) GIT1 mRNA expression in AGS cells after transfection. *P<0.01 compared with Ctrl, ^#P<0.01 compared with sh-Ctrl, n=3. (h) GIT1 protein expression after transfection with MeCP2 shRNA or MeCP2 overexpression vector.