Table 1. Correlations of high-level mitochondrial EGFR and Tid1-S with the pathological features of 35 NSCLC patientsa.
| Characteristics |
Level of mitEGFR |
Level of mitTid1-S |
Levels of mitTid1-S and mitEGFR |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Lowb (N=6) | Highc (N=29) | P-value | Lowb (N=2) | Highc (N=33) | P-value | Lowb (N=2) | Highc (N=29) | P-value | |
| Age (years) | |||||||||
| ⩽60 | 3 | 6 | 0.13 | 1 | 8 | 0.42 | 1 | 7 | 0.41 |
| >60 | 3 | 23 | 1 | 25 | 1 | 22 | |||
| Gender | |||||||||
| Male | 3 | 12 | 0.70 | 2 | 13 | 0.09 | 1 | 12 | 0.81 |
| Female | 3 | 17 | 0 | 20 | 1 | 17 | |||
| T staged | |||||||||
| T1 | 3 | 6 | 0.13 | 2 | 7 | 0.01* | 2 | 6 | 0.01* |
| T2–T4 | 3 | 23 | 0 | 26 | 0 | 23 | |||
| N stagee | |||||||||
| N=0 | 4 | 8 | 0.06 | 2 | 10 | 0.04* | 2 | 8 | 0.03* |
| N>0 | 2 | 21 | 0 | 23 | 0 | 21 | |||
| M stagef | |||||||||
| M=0 | 6 | 16 | 0.04* | 2 | 20 | 0.26 | 2 | 16 | 0.21 |
| M>0 | 0 | 13 | 0 | 13 | 0 | 13 | |||
| Overall stage | |||||||||
| I | 4 | 5 | 0.01* | 2 | 7 | 0.01* | 2 | 5 | <0.01** |
| II-/IV | 2 | 24 | 0 | 26 | 0 | 24 | |||
| Gradeg | |||||||||
| 1 | 4 | 4 | <0.01** | 2 | 6 | <0.01** | 2 | 4 | <0.01** |
| 2–3 | 2 | 25 | 0 | 27 | 0 | 25 | |||
a
As assessed by χ2-test.
b
Low: tumors showing little or no staining in mitochondria.
c
High: tumors showing intense staining in mitochondria.
d
T stage: the size and extent of the main tumor.
e
N stage: the number of nearby lymph nodes that have cancer cells.
f
M stage: whether the cancer has metastasized.
g
Grade: to classify cancer cells based on their appearance and behavior when viewed under a microscope.