Figure 1.
HMG-CoA reductase inhibitory activity of ethanol and DCM : M bark extracts of Ceylon cinnamon. Data represented as mean ± SEM (n = 3); mean % inhibition values of ethanol and DCM : M bark extracts superscripted by different letters at each concentration were significantly different at p < 0.05. Mean IC50 values of ethanol bark, DCM : M, and pravastatin were 153.07 ± 8.38, 277.13 ± 32.18, and 0.50 ± 0.05 μg/mL, respectively. Ethanol bark, DCM : M bark, and pravastatin r2 = 0.97, 0.99, and 0.99, respectively. DCM : M: dichloromethane : methanol.