Table 3.
Cholesterol micellization inhibitory activity of bark extracts and EGCG.
| Extract/Std | % inhibition of cholesterol solubility in micelles |
µg/mL IC50 |
||
|---|---|---|---|---|
| Concentration (µg/mL) | ||||
| 250 | 500 | 1000 | ||
| EGCG | 55.16 ± 0.91 | 69.78 ± 1.82 | 96.75 ± 1.70 | 150.98 ± 18.72e |
| Ethanol bark | 49.48 ± 0.78 | 69.48 ± 0.81 | 98.09 ± 0.51 | 231.96 ± 9.22d |
| DCM : M bark | 19.36 ± 2.04 | 62.15 ± 1.06 | 73.94 ± 0.87 | 478.89 ± 9.27c |
Data represented as mean ± SEM (EGCG n = 3; ethanol bark and DCM : M bark n = 6 each). IC50 values in a column superscripted by different letters are significantly different at p < 0.05. EGCG, ethanol bark, and DCM : M bark are r2 = 1.00, 0.99, and 0.90, respectively. DCM : M: dichloromethane : methanol; EGCG: epigallocatechin gallate.