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. 2017 Jul 7;28(14):1894–1900. doi: 10.1091/mbc.E17-01-0053

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© 2017 Hall et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 5: — (A, B) Effect of oxidative stress on force modulation of SMCs for both I-O and O-I modes (p < 0.01 for both cases). Inset in A shows the higher migration rate of cells under oxidative conditions (p < 0.01). (C, D) Representative transient profiles of cyclic perturbation, showing decrease in force with increasing number of cycles and the detachment of the cell from the fiber in the O-I mode (arrow). (E) I-O forces decrease with increasing number of cycles. (F) O-I forces decrease with cyclic perturbation.