Table 3.

Multivariable Model Predicting Any Treatment Initiation.

	OR (95% CI)	p value
Site
Site 1	Ref.	< .001
Site 2	1.77 (1.45 – 2.16)
Site 3	2.10 (1.72 – 2.57)
Age at index event
12–14	Ref.	.008
15–17	0.78 (0.67 – 0.92)
18–20	0.83 (0.70 – 0.99)
Race
White/Caucasian	Ref.	< .001
Black/African American	0.55 (0.43 – 0.71)
Asian/Pacific Islander	0.54 (0.39 – 0.77)
Other/Multi-racial	0.76 (0.58 – 0.99)
Missing	0.63 (0.54 – 0.75)
PHQ score at index event
None (new diagnosis only as index event)	Ref.	< .001
Moderate (10–14)	0.99 (0.82 – 1.21)a
Mod-Severe (15–19)	1.46 (1.19 – 1.80)
Severe (20+)	2.14 (1.65 – 2.79)
Diagnosis at index event
No diagnosis (positive PHQ-9 only as index event)	Ref.	< .001
Major Depression/Dysthymia	2.65 (2.20 – 3.20)
Unspecified Depression/Adjustment disorderb	1.75 (1.43 – 2.14)

Notes: OR = Odds ratio; CI = confidence interval; PHQ = Patient Health Questionnaire;

^aNot significantly different than the referent group

^bOnly those adjustment disorders with depressive symptoms included