Fig. 3.

An example of excitation tailored to three specific resonances. A and B: The pulse shape, optimized in under 3 s using the toggling frame method. C: Simulated magnetization trajectories for resonances at −20, 0, and 100 ppm, respectively. All three trajectories end up with a y-component of at least 0.997. D: Experimental spectra obtained by moving the carrier frequency around the single resonance of 5-F-Tryptophan. The upper spectra were recorded with the optimal control pulse, and the lower used a hard pulse at the same maximum RF field strength (20 kHz). All processing settings, in particular phase and display settings, are the same for all spectra. The optimal control pulse is clearly more suited to simultaneous in-phase excitation of these three resonances.