Table 1. Spontaneous behavior scoring description and rubric.

The summed behavioral scores (body, head and eye) were averaged to determine a composite score for each evaluation period.

Behavior	Score	Description
Posture	4	Lateral recumbency, one shoulder and hip in full contact with floor, and/or 4 limbs extended
	3	Front limbs sternal, hip shifted laterally, hind limbs extended
	2	Sternal recumbency, hip and/or shoulder shifted laterally, limbs tucked under body, neck turned laterally
	1	Sternal recumbency, 4 limbs square
	0	Sitting
	−1	Standing motionless >3 s
	−2	Continuously walking
	−3	Circling, digging, pawing
Head	1	Head down
	0	Head up
Eyes	3	Sunken, unfocused
	2	Closed > 60 s
	1	Closed > 10 s <60 s
	0	Open > 10 s
	−1	Scanning, 3+ movements of pupil from center position/s