Table 1.

RPE thickness relative to the ELM descent in neovascular AMD eyes

RPE Morphology	−500 µm from ELM descent	−100 µm from ELM descent
	Thickness, mean ± SD, µm; N		p value, − 500 vs −100	Thickness, mean ± SD, µm; N
Overall	11.8 ± 6.0; 23	12.8 ± 6.2; 26	0.2847	12.3 ± 6.1; 27*
Non-uniform	10.6 (n/a); 1	---	---	10.6 (n/a); 1
Very non- uniform	10.8 ± 3.0; 20	11.0 ± 3.9; 20	0.8360	10.9 ± 3.5; 25
Sloughed	23.9 ± 8.9; 4	17.4 ± 4.5; 6	0.0600	19.8 ± 6.8; 8
Shedding	---	---	---
Bilaminar	17.7 ± 8.2; 2	22.3 ± 4.5; 6	0.3104	21.2 ± 5.4; 7
Vacuolated	---	---	---
Intraretinal	---	---	---

Notes: assessments were made in 27nv-AMD eyes lacking subretinal scar within ± 500 µm of the ELM descent and including eyes with sub-RPE scar

N indicates the number of donors in which measurements were made.

Thicknesses were not recorded for ‘dissociated’ RPE within the atrophic area.

P-value obtained via general estimating equations

SD, standard deviation

n/a, not applicable

^*For 22 eyes accessioned before 2006, overall mean RPE thickness was 12.3 ± 6.2 µm