Table 2.

Basal laminar deposit thickness relative to the ELM descent in neovascular AMD eyes

RPE Morphology	−500 µm from ELM descent	−100 µm from ELM descent	−500 µm vs −100 µm	+100 µm from ELM descent	+500 µm from ELM descent	+500 µm vs +100 µm	Overall −500 µm and −100 µm	Overall +100 µm and +500 µm
RPE Morphology	Thickness, mean ± SD, µm; N		p value	Thickness, mean ± SD, µm; N		p value	Thickness, mean ± SD, µm; N
Overall	3.7 ± 3.7; 23	2.9 ± 3.2; 26	0.0844	3.3 ± 4.7; 27	4.2 ± 5.0; 26	0.0246	3.2 ± 3.5; 27^*	3.7 ± 4.8; 27
Non-uniform	2.2 (n/a); 1	---	---	---	---	---	2.2 (n/a); 1	---
Very non-uniform	4.0 ± 3.9; 20	2.9 ± 3.4; 20	0.0404	---	---	---	3.5 ± 3.7; 25	---
Sloughed	2.6 ± 2.6; 4	4.5 ± 3.7; 6	0.2204	---	---	---	3.8 ±3.3; 8	---
Shedding	---	---	---	---	---	---	---	---
Bilaminar	1.7 ± 2.4; 2	1.3 ± 1.7; 6	0.7621	---	---	---	1.4 ± 1.7; 7	---
Vacuolated	---	---	---	---	---	---	---	---
Intraretinal	---	---	---	---	---	---	---	---
Dissociated	---	---	---	7.5 ± 6.5; 10	6.7 ± 7.1; 9	0.6461	---	7.2 ± 6.6; 12
Atrophy with BLamD	---	---	---	3.4 ± 2.0; 11	5.5 ± 3.7; 16	0.0407	---	4.6 ± 3.2; 18
Atrophy without BLamD	---	---	---	0; 10	0.6 ± 2.3; 12	0.2407	---	0.3 ± 1.6; 15

Notes: assessments were made in 27nv-AMD eyes lacking subretinal scar within ± 500 µm of the ELM descent and including eyes with sub-RPE scar

N indicates the number of donors in which measurements were made.

P-value obtained via general estimating equations

SD, standard deviation

n/a, not applicable

For 22 eyes accessioned before 2006, overall mean BLamD thickness was 2.9 ± 3.3 µm