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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Retina. 2016 Dec;36(Suppl 1):S26–S39. doi: 10.1097/IAE.0000000000001330

Table 3.

RPE + Basal laminar deposit thickness relative to the ELM descent in nvAMD

RPE
Morphology
−500 µm from ELM
descent
−100 µm from ELM
descent
−500 µm vs −100
µm
Overall
Thickness in µm, mean ± SD; N p-value Thickness in
µm,
mean ± SD; N
Overall 15.7 ± 7.0; 23 15.4 ± 7.7; 26 0.9109 15.4 ± 7.3; 27*
Non-uniform 12.8 (n/a); 1 --- --- 12.8 (n/a); 1
Very non-
uniform
14.8 ± 5.3; 20 13.9 ± 5.8; 20 0.3788 14.3 ± 5.5; 25
Sloughed 26.6 ± 8.4; 4 21.8 ± 7.9; 6 0.1408 23.5 ± 8.0; 8
Shedding --- --- --- ---
Bilaminar 19.4 ± 10.6; 2 23.6 ± 3.6; 6 0.4423 22.6 ± 5.4; 7
Vacuolated --- --- --- ---
Intraretinal --- --- --- ---

Notes: Mean RPE + BLamD thickness by RPE grades in 27 nvAMD eyes from 27donors

N indicates the number of donors in which measurements were made.

P-value obtained via general estimating equations

SD, standard deviation

n/a, not applicable

*

For 22 eyes accessioned before 2006, overall mean RPE+BLamD thickness was 15.0 ± 7.4 µm