Table 3.
RPE + Basal laminar deposit thickness relative to the ELM descent in nvAMD
| RPE Morphology | −500 µm from ELM descent | −100 µm from ELM descent | −500 µm vs −100 µm | Overall | 
|---|---|---|---|---|
| Thickness in µm, mean ± SD; N | p-value | Thickness in µm, mean ± SD; N | ||
| Overall | 15.7 ± 7.0; 23 | 15.4 ± 7.7; 26 | 0.9109 | 15.4 ± 7.3; 27* | 
| Non-uniform | 12.8 (n/a); 1 | --- | --- | 12.8 (n/a); 1 | 
| Very non- uniform | 14.8 ± 5.3; 20 | 13.9 ± 5.8; 20 | 0.3788 | 14.3 ± 5.5; 25 | 
| Sloughed | 26.6 ± 8.4; 4 | 21.8 ± 7.9; 6 | 0.1408 | 23.5 ± 8.0; 8 | 
| Shedding | --- | --- | --- | --- | 
| Bilaminar | 19.4 ± 10.6; 2 | 23.6 ± 3.6; 6 | 0.4423 | 22.6 ± 5.4; 7 | 
| Vacuolated | --- | --- | --- | --- | 
| Intraretinal | --- | --- | --- | --- | 
Notes: Mean RPE + BLamD thickness by RPE grades in 27 nvAMD eyes from 27donors
N indicates the number of donors in which measurements were made.
P-value obtained via general estimating equations
SD, standard deviation
n/a, not applicable
For 22 eyes accessioned before 2006, overall mean RPE+BLamD thickness was 15.0 ± 7.4 µm