Table 4.

Comparison of microstructure in neovascular AMD and geographic atrophy eyes

#	Metric	Neovascular AMD (N=27)	Geographic atrophy* (N=13)	P
1	% of RPE phenotypes ≥ ’very non-uniform’ in non-atrophic area
	−500 µm	97.7%	72.2%	0.002 7
	−100 µm	100.0%	96.8%	n.s.
2	RPE phenotypes in atrophic area	‘dissociated’, ‘subducted’, ‘melanotic’ **, ‘entombed’ **, ‘entubulated’ †	‘dissociated’, ‘subducted’, ‘entubulated’ †	--
3	BLamD thickness, non-atrophic area	3.25 ± 3.46 µm	7.99 ± 7.49 µm	0.017
4	BLamD thickness, atrophic area	3.70 ± 4.81 µm	6.63 ± 6.17 µm	0.047
5	Shape of ELM descent
	Oblique	47.9%	31.9%	0.046
	Curved +   reflected	52.1%	68.1%

Notes:

^*30;

^**29;

^†53

±500, ±100, distances from ELM descent in µm, negative is non-atrophic, positive is atrophic;

Statistical evaluation: n.s., not significantat p< 0.05 level.

Line 3–4 thicknesses in given locations were pooled across all RPE phenotypes.