Table 1.
Characteristics of Patients With T1D
| Type 1 Diabetes | Autoantibodies | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Case ID | Age, y | Sex | BMI, kg/m2 | GADA Result | IA 2A Result | MIAA Result | Zn T8A Result | Total Positive Autoantibody Count | Duration of Diabetes, y | Insulin Status | |
| 1 | 6062 | 10.7 | M | 21.9 | N/A | N/A | N/A | N/A | N/A | 6 | No insulin |
| 2 | 6063 | 4.4 | M | 23.8 | − | − | + | − | 1 | 3 | No insulin |
| 3 | 6064 | 19.6 | F | 22.6 | + | + | + | − | 3 | 9 | No insulin |
| 4 | 6089 | 14.3 | M | 26 | − | − | + | − | 1 | 8 | No insulin |
| 5 | 6083 | 15.2 | F | 18.4 | − | − | + | − | 1 | 11 | No insulin |
| 6 | 6087 | 17.5 | M | 21.9 | − | − | + | + | 2 | 4 | No insulin |
| 7 | 6145 | 18 | M | 23.1 | + | − | + | + | 3 | 11 | No insulin |
| 8 | 6148 | 17.1 | M | 23.9 | + | − | + | − | 2 | 7 | No insulin |
| 9 | 6261 | 16 | M | 20.7 | + | − | + | − | 2 | 14 | No insulin |
| 10 | 6360 | 4.8 | F | 26.1 | − | − | + | − | 1 | 2.5 | No insulin |
| 11 | 6046 | 18.8 | F | 25.2 | − | + | − | + | 2 | 8 | Abundant insulin+ islets |
| 12 | 6049 | 15 | F | 20.8 | + | − | + | − | 2 | 10 | Rare insulin + cells |
| 13 | 6084 | 14.2 | M | 26.3 | − | − | + | − | 1 | 4 | Some insulin+ cells in islets, patchy |
| 14 | 6195 | 19.2 | M | 23.7 | + | + | + | + | 4 | 5 | Rare insulin + cells |
| 15 | 6243 | 13 | M | 21.3 | − | − | + | − | 1 | 5 | Abundant insulin+ islets |
| 16 | 6265 | 11 | M | 12.9 | + | − | + | − | 2 | 8 | Rare insulin + cells |
| 17 | 6268 | 12 | F | 26.6 | − | − | + | − | 1 | 3 | Rare insulin + cells |
| 18 | 6306 | 19 | M | 24.5 | − | − | + | − | 1 | 5 | Abundant insulin+ islets |
| 19 | 6342 | 14 | F | 24.3 | − | + | + | − | 2 | 2 | Abundant insulin+ islets |
| Mean | 14.9 | 22.8 | |||||||||
| SEM | 0.9 | 0.8 | |||||||||
Abbreviations: +, positive; −, negative; F, female; GADA, glutamic acid decarboxylase; IA 2A, IA-2 antibody; M, male; MIAA, micro insulin autoantibody; N/A, not applicable; SEM, standard error of the mean; Zn T8A, zinc transporter antibody.