Table 1. Clinical characteristics of study subjects.
| cirrhosis |
|||
|---|---|---|---|
| control | compensated | decompensated | |
| n | 20 | 59 | 21 |
| Age (y) | 67 (66-69) | 58 (53-64) | 58 (50-66) |
| Male/female | 15/5 | 42/17 | 16/5 |
| Total cholesterol (mg/dL) | 169 (152-188) | 173 (134-209) | 86 (64-123)***†† |
| Triglycerides (mg/dL) | 103 (70-145) | 81 (60-105) | 77 (62-123) |
| LDL-cholesterol (mg/dL) | 78 (60-102) | 107 (72-133) | 63 (42-74)†† |
| HDL-cholesterol (mg/dL) | 65 (55-80) | 44 (25-61)* | 10 (6-19)***†† |
| Apolipoprotein A-I (mg/dL) | 79 (57-113) | 37 (27-52)*** | 17 (15-24)***† |
| CRP (mg/L) | 2 (1-3) | 3 (1-5) | 25 (12-46)***†† |
| Child-Pugh Score | - | 5 (5-6) | 10 (8-12) |
| MELD Score | - | 10 (8-14) | 17 (15-19) |
| Etiology of liver disease (%) | |||
| Alcohol | - | 49.1 | 95.2 |
| Viral infection | - | 21.1 | 4.8 |
| Other | - | 29.8 | - |
| Albumin$ (g/dL) | - | 4.0 ± 0.6 | 2.9 ± 0.7† |
| Bilirubin$ (mg/dL) | - | 1.7 ± 1.6 | 5.3 ± 4.7† |
| Creatinine$ (mg/dL) | 0.9 ± 0.3 | 0.9 ± 0.2 | 1.0 ± 0.6 |
Values are given as medians with the interquartile range. $Values are given as mean ± SD. CRP, C-reactive protein. *P < 0.05, ***P < 0.001 vs. control. †P < 0.01, ††P < 0.001 vs. compensated.