Table 2.
Voice Handicap Index, Auditory-Perceptual Evaluation, and Sinonasal Outcome Test Measures.a
| p Value | |||||||
|---|---|---|---|---|---|---|---|
|
|
|||||||
| CF (n = 17) |
Non-CF Sinusitis (n = 10) |
Healthy Individuals (n = 10) |
Overall Comparison |
CF vs Non-CF Sinusitis |
Non-CF Sinusitis vs Healthy |
CF vs Healthy |
|
| VHI-10, mean score (SD) [95% CI] | 7.94 (5.06) [5.34–10.5] | 5.4 (4.9) [2.45–9.35] | 1.7 (2.1) [0.19–3.21] | .005 | .31 | .02 | .001 |
| CAPE-V score, mean (SD) [median], mm Overall severity (R = 0.78) | 28.7 (9.70) [29.3] | 19.3 (4.98) [18.9] | 15.7 (7.0) [15.3] | .0005 | .005 | .17 | .006 |
| Breathiness (R = 0.71) | 9.74 (8.24) [9.5] | 7.20 (4.62) [7.25] | 2.93 (1.96) [2.5] | .06 | |||
| Roughness (R = 0.80) | 21.7 (12.6) [18.7] | 16.5 (6.64) [14.8] | 12.9 (6.9) [12.3] | .094 | |||
| Strain (R = 0.77) | 19.2 (10.7) [16.2] | 11.0 (4.03) [11.8] | 11.28 (4.62) [10.3] | .08 | |||
| Glottal fry (R = 0.78) | 15.7 (11.6) [13.7] | 15.6 (11.3) [14.8] | 15.4 (10.4) [14.4] | .99 | |||
| SNOT-20, mean score (SD) [95% CI] | 33.9 (16.8) [24.9–42.8] | 39.1 (19.9) [24.9–53.3] | 5.20 (5.35) [1.37–9.03] | <.0001 | .47 | .0001 | <.0001 |
Abbreviations: CAPE-V, Consensus Auditory-Perceptual Evaluation of Voice; CF, cystic fibrosis; R, intraclass correlation coefficient for raters; SD, standard deviation; SNOT-20, 20-item Sinonasal Outcome Test; VHI-10, 10-item Voice Handicap Index.
a
Comparisons were performed using 1-way analysis of variance followed by the Student t test for pairwise comparisons of VHI-10 and SNOT-20, as well as for CAPE-V using Kruskal-Wallis followed by the Mann-Wilson rank-sum test for pairwise comparisons.