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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Neurobiol Aging. 2017 Jun 3;57:170–177. doi: 10.1016/j.neurobiolaging.2017.05.020

Table 2.

The expression of piRNAs correlated with the genome-wide significant replicated risk SNPs for AD (p<0.008)

Gene (chr) LOC105373605 (chr2) APOJ (chr8) SORL1 (chr11) RNU6-560P (chr11) SLC24A4 (chr14) NECTIN2-TOMM40-APOE-APOC1 (chr19) CD33 (chr19)
SNPs rs6733839 rs744373 rs7561528 rs2279590 rs9331896 rs11218343 rs3851179 rs10792832 rs10498633 rs2075650 rs429358 rs4420638 ε2/ε3/ε4 rs3865444
In cases and controls
DQ571669 VPS53 3.7×10−3 4.7×10−3
DQ573352 ABCA13 7.3×10−3
DQ573721 - 1.1×10−3
DQ574452 to_KCNK10 6.0×10−3
DQ577835 FAM225B 3.0×10−3
DQ579851 to_PGPEP1L 8.8×10−4 2.9×10−3
DQ581441 to_CHST1 3.5×10−3
DQ581734 TYSND1 2.8×104 3.4×104
DQ583613 to_HIST1H4H 6.7×10−3
DQ584325 to_C2CD4B 2.2×10−3
DQ584637 AGAP1 1.2×10−3
DQ584879 CYP19A1 7.5×10−3
DQ584936 to_METTL14 3.5×10−3
DQ592330 to_ELFN2 3.3×104
DQ594768 to_CHEK2P2 3.5×10−3
DQ597396 to_UBASH3B 6.1×10−3
DQ597397 to_UBASH3B 2.7×104 6.0×10−4
DQ597401 to_VN1R10P 3.1×10−3 5.4×10−3
DQ597402 to_VN1R10P 4.1×10−3 5.9×10−3
DQ597403 to_VN1R10P 3.4×10−3 4.6×10−3
DQ597886 to_ILF2 7.5×10−3
DQ598571 to_CHST1 4.8×10−3
DQ600318 LRRC37A3 7.0×10−3 2.3×104
In controls
DQ574023 to_B3GALTL 9.2×105
DQ576492 LINC00837 3.6×10−3
DQ577835* FAM225B 5.1×10−3
DQ584879* CYP19A1 6.4×10−3
DQ586113 to_EVPLL 3.0×10−3
DQ590261 ANKRD20A19P 1.2×10−3 1.2×10−3
DQ597109 to_HIST1H4H 5.7×10−3
DQ597397* to_UBASH3B 3.8×10−3 4.6×10−3 4.6×10−3
DQ597402* to_VN1R10P 5.4×10−3 5.4×10−3
DQ598028 FLJ25328 2.9×10−3
DQ599147 CTC1 6.0×10−3
DQ599205 KIAA0319L 5.9×10−3
In cases
DQ597973 to C11orf87 7.3×10−3
DQ597402* to_VN1R10P 7.2×10−3
DQ598571* to_CHST1 3.8×10−3
DQ581441* to_CHST1 4.9×10−3
DQ600513 to C11orf87 6.4×10−3

The correlations with p<α=5×10−4 (=0.05/103 piRNAs) were bold; “to”, proximate to;

*

, appears at least twice in this table.