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. Author manuscript; available in PMC: 2017 Aug 3.
Published in final edited form as: Basic Res Cardiol. 2016 Apr 4;111(3):29. doi: 10.1007/s00395-016-0547-4

Fig. 2.

Fig. 2

Mitochondrial production of reactive oxygen species (ROS) in Zucker lean (ZLN), Zucker obese fatty (ZOF), ZLN + mt-tat-ExoIII, and ZOF + mt-tat-EndoIII during state 3 and state 4 respiration. Top representative EPR signals from the four groups. Bottom quantified EPR signals in the four groups. ZOF produced greater amount of ROS than ZLN (P <0.05). Treatment of mt-tat-ExoIII in ZLN increased ROS production compared to ZLN; whereas treatment of mt-tat-EndoIII in ZOF decreased ROS production compared to ZOF. Overall ROS production was higher during state 4 vs. state 3. N = 5 for all measurements