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Parametric study of actomyosin bond stiffness (k = 10, 100, and 2000 pN/µm) using the control segment connected to a linear spring. (a) Normalized contractile force F* = F/ζ as a function of normalized external stiffness K* = K/2000. One sees that the stiffness sensing ability of the SFs increases with bond stiffness k. (b) Activation parameter a versus time for K* = 0.5. The rate of cross-bridge activation also increases with bond stiffness k.
