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. 2017 Apr 1;8(28):45200–45212. doi: 10.18632/oncotarget.16778

Figure 1. CdM derived from MSCs promotes angiogenesis.

Figure 1

(A) Representative images of capillary-like structures and quantitative analysis of the total tube length (4× magnification microscopic fields); (B) Representative images of HUVEC spheroids sprouting and quantitative analysis of the cumulative sprout length per spheroid; (C) Representative gross look of Matrigel plugs which were implanted subcutaneously in mice for 14 days; (D) Hemoglobin content in the Matrigel plugs; (E) The neovasculature in Matrigel was visualized by immunofluorescence staining of CD31. Quantification of the CD31-positive cells in Matrigel plugs were determined by pixel density (*P < 0.05 vs CON).