Table 10. Relation of SNPs identified in the present study to the serum concentration of uric acid.
| SNP | Serum uric acid (μmol/L) | P | |||
|---|---|---|---|---|---|
| Associated with serum uric acid | |||||
| rs121907892 | G/A (W258*) | GG | GA | AA | |
| 333 ± 93 | 230 ± 79 | 50 ± 18 | <1.0 × 10−23 | ||
| rs188780113 | G/A (R478C) | GG | GA | AA | |
| 331 ± 93 | 283 ± 103 | 197 ± 105 | <1.0 × 10−23 | ||
| rs505802 | G/A | GG | GA | AA | |
| 334 ± 92 | 318 ± 98 | 291 ± 97 | <1.0 × 10−23 | ||
| rs55975541 | G/A (R1237W) | GG | GA | AA | |
| 332 ± 94 | 319 ± 95 | 306 ± 111 | 3.62 × 10−12 | ||
| rs3775948 | G/C | GG | GC | CC | |
| 335 ± 93 | 329 ± 94 | 314 ± 97 | 1.37 × 10−12 | ||
| rs3733591 | T/C (H265R) | TT | TC | CC | |
| 324 ± 94 | 331 ± 96 | 339 ± 93 | 6.36 × 10−6 | ||
| Associated with hyperuricemia | |||||
| rs115445569 | C/T (R64Q) | CC | CT | TT | |
| 328 ± 95 | 341 ± 101 | 345 ± 170 | 0.1012 | ||
| rs116911833 | G/A (T80M) | GG | GA | AA | |
| 328 ± 95 | 324 ± 89 | 352 ± 109 | 0.5779 | ||
| rs60854092 | T/A (F1689I) | TT | TA | AA | |
| 328 ± 94 | 325 ± 98 | 322 ± 121 | 0.5501 | ||
Data were compared among genotypes by one-way ANOVA. Based on Bonferroni's correction, P values of <0.0056 (0.05/9) were considered statistically significant and are shown in bold.