Table 6. Characteristics of the study subjects in the EWAS for hyperuricemia.
| Characteristic | Hyperuricemia | Controls | P |
|---|---|---|---|
| No. of subjects | 2045 | 9641 | |
| Age (years) | 59.6 ± 12.2 | 58.3 ± 13.2 | <0.0001 |
| Sex (male/female, %) | 86.7/13.4 | 52.9/47.1 | <0.0001 |
| Body mass index (kg/m2) | 24.3 ± 3.7 | 23.1 ± 3.4 | <0.0001 |
| Current or former smoker (%) | 53.7 | 34.7 | <0.0001 |
| Hypertension (%) | 68.9 | 47.2 | <0.0001 |
| Diabetes mellitus (%) | 31.5 | 23.0 | <0.0001 |
| Dyslipidemia (%) | 77.6 | 58.4 | <0.0001 |
| CKD (%) | 44.8 | 17.9 | <0.0001 |
| Serum uric acid (μmol/L) | 453 ± 83 | 296 ± 67 | <0.0001 |
Quantitative data are means ± SD and were compared between subjects with hyperuricemia and controls with the Mann-whitney u test. Categorical data were compared between the two groups with the pearson's test chi-square test. Based on Bonferroni's correction, a P value of <0.0056 (0.05/9) was considered statistically significant.