Table 4. Multivariate Cox analysis of relapse-free and overall survival for TIAM1 variant, MYCN amplification and age at diagnosis.
Variables | Multivariate Analysis | |||||
---|---|---|---|---|---|---|
Relapse-free survival | Overall survival | |||||
HR | 95% CI | p | HR | 95% CI | p | |
*Age | 1.017 | 1.008-1.025 | 0.0002 | 1.010 | 1.001-1.018 | 0.022 |
TIAM1 variant | ||||||
No | 1.000 | 0.025-0.833 | 0.021 | 1.000 | 0.028-0.206 | 0.006 |
Yes | 0.222 | 0.083 | ||||
MYCN amplification | ||||||
No | 1.000 | 0.723-2.514 | 0.321 | 1.000 | 1.368-5.029 | 0.004 |
Yes | 1.375 | 2.623 |
Abbreviations: HR, Hazard Ratio; CI, confidence interval
*Age was consider as continuous variable measured in months