Figure 1. Downregulation of HERG protein expression by ATO and Ang II.

Immunoblot analysis of HERG protein expression in NMCMs pretreated with (A) ATO (2 μM) for 24 h and (B) Ang II (100 nM) for 12 or 24 h. Quantitative densitometric analyses of the HERG protein at 135 kDa or 155 kDa are shown in the lower panel. The data represent the mean ± SEM normalized with control (Ctrl) of three separate experiments. *P < 0.05 versus control group.