Table 1. Correlation between miR-874 expression and different clinicopathological features in breast cancer.
Variable | Cases (n) | Expression level of miR-874 | P-value | |
---|---|---|---|---|
Low (n, %) | High (n, %) | |||
Ages | ||||
< 60 | 590 | 291 | 299 | 0.603 |
≥ 60 | 499 | 254 | 245 | |
ER | ||||
positive | 842 | 435 | 407 | 0.049* |
negative | 247 | 110 | 137 | |
PR | ||||
positive | 737 | 368 | 369 | 0.913 |
negative | 435 | 177 | 175 | |
Lymph node | ||||
negative | 504 | 252 | 252 | 0.001* |
1∼3 | 386 | 179 | 207 | |
4∼9 | 123 | 56 | 67 | |
≥ 10 | 76 | 58 | 18 | |
Distant metastasis | ||||
No | 1066 | 531 | 535 | 0.294 |
Yes | 23 | 14 | 9 | |
Tumor sizes | ||||
< 2 cm | 291 | 132 | 159 | 0.062 |
≥ 2 cm | 798 | 13 | 385 | |
TNM staging | ||||
I.II | 819 | 392 | 427 | 0.012* |
III IV | 270 | 153 | 117 |
*P < 0.05 calculated with Pearson chi2 test.