Table 3. Comparison of methylation level between breast cancer and adjacent normal tissue in each CpG site.
| CpG sites | Number of pairs | Tissue types | Mean methylation level ± SD | Paired t value |
|---|---|---|---|---|
| CpG1,2 | 19 | para-tumor breast cancer tissue |
0.7684 ± 0.090 0.8421 ± 0.083 |
2.607*(0.013) |
| CpG4,5 | 19 | para-tumor breast cancer tissue |
0. 7784 ± 0.062 0. 8442 ± 0.075 |
2.939*(0.006) |
| CpG6 | 19 | para-tumor breast cancer tissue |
0.5142 ± 0.226 0.7400 ± 0.268 |
2.805*(0.008) |
| CpG7 | 19 | para-tumor breast cancer tissue |
0.7205 ± 0.127 0.8232 ± 0.125 |
2.504*(0.017) |
| CpG8 | 19 | para-tumor breast cancer tissue |
0.8495 ± 0.091 0.9137 ± 0.092 |
2.166*(0.037) |
| CpG9 | 19 | para-tumor breast cancer tissue |
0.7568 ± 0.080 0.7663 ± 0.0756 |
0.375(0.710) |