Table 9. VDR haplotype frequencies (%) in cases and controls and risk of GCA.
| Haplotypes | Cases (n = 660) | Controls (n = 1216) | Crude OR (95% CI) | p | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| VDR Trs2107301Crs2228570Crs1989969Grs11568820 | 114 | 17.27 | 181 | 14.88 | 1.00 | |
| VDR Trs2107301Trs2228570Crs1989969Grs11568820 | 75 | 11.36 | 174 | 14.31 | 0.68 (0.48-0.98) | 0.038 |
| VDR Trs2107301Crs2228570Crs1989969Ars11568820 | 54 | 8.18 | 123 | 10.12 | 0.70 (0.47-1.04) | 0.075 |
| VDR Trs2107301Trs2228570Trs1989969Ars11568820 | 74 | 11.21 | 114 | 9.38 | 1.03 (0.71-1.50) | 0.875 |
| VDR Crs2107301Crs2228570Crs1989969Grs11568820 | 59 | 8.94 | 115 | 9.46 | 0.82 (0.55-1.21) | 0.305 |
| VDR Trs2107301Trs2228570Crs1989969Ars11568820 | 44 | 6.67 | 86 | 7.07 | 0.81 (0.53-1.25) | 0.346 |
| VDR Crs2107301Crs2228570Crs1989969Ars11568820 | 31 | 4.70 | 65 | 5.35 | 0.76 (0.47-1.23) | 0.264 |
| VDR Trs2107301Crs2228570Trs1989969Grs11568820 | 29 | 4.39 | 63 | 5.18 | 0.73 (0.44-1.20) | 0.218 |
| VDR Trs2107301Crs2228570Trs1989969Ars11568820 | 36 | 5.45 | 62 | 5.10 | 0.92 (0.58-1.48) | 0.736 |
| VDR Trs2107301Trs2228570Trs1989969Grs11568820 | 34 | 5.15 | 58 | 4.77 | 0.93 (0.57-1.51) | 0.771 |
| VDR Crs2107301Trs2228570Crs1989969Grs11568820 | 27 | 4.09 | 50 | 4.11 | 0.86 (0.51-1.45) | 0.565 |
| VDR Crs2107301Crs2228570Trs1989969Grs11568820 | 15 | 2.27 | 31 | 2.55 | 0.77 (0.40-1.49) | 0.433 |
| VDR Crs2107301Trs2228570Crs1989969Ars11568820 | 20 | 3.03 | 29 | 2.38 | 1.10 (0.59-2.03) | 0.773 |
| VDR Crs2107301Trs2228570Trs1989969Ars11568820 | 17 | 2.58 | 25 | 2.06 | 1.08 (0.56-2.09) | 0.820 |
| VDR Crs2107301Crs2228570Trs1989969Ars11568820 | 24 | 3.64 | 23 | 1.89 | 1.66 (0.89-3.07) | 0.109 |
| VDR Crs2107301Trs2228570Trs1989969Grs11568820 | 7 | 1.06 | 17 | 1.40 | 0.65 (0.26-1.63) | 0.361 |
With the order of VDR rs2107301 T>C, rs2228570 C>T, rs1989969 C>T and rs11568820 G>A in gene position.