Table 3. Multivariate analysis of the training set.

	Model-TNM			Model-TRM
	HR	95% CI	p	HR	95% CI	p
Age	1.02	1.01 to 1.03	<0.001	1.02	1.01 to 1.03	<0.001
Location			<0.001			<0.001
Lower	ref			ref
Middle	1.37	1.09 to 1.73		1.43	1.13 to 1.81
Upper	1.57	1.31 to 1.90		1.55	1.29 to 1.86
Pathological type	1.25	1.05 to 1.50	0.028	1.23	1.03 to 1.46	0.022
NO. of examined LNs	0.97	0.96 to 0.98	0.013
Depth of invasion			<0.001			<0.001
Mucosa or submucosa	ref			ref
Proper muscle	4.76	1.69 to 13.41		5.01	1.78 to 14.11
Subserosa	6.13	2.23 to 16.86		6.11	2.22 to 16.81
Serosa	10.84	4.00 to 29.36		10.69	3.94 to 28.98
Adjacent invasion	15.97	5.83 to 43.75		16.18	5.90 to 44.36
mLNR						<0.001
0				ref
1				1.49	0.98o 2.27
2				2.14	1.44 to 3.18
3				3.41	2.31 to 5.03
4				5.90	4.04 to 8.61
5				6.56	4.19 to 10.27
mLNS			<0.001
0	ref
1	1.87	1.40 to 2.49
2	2.54	1.94 to 3.33
3a	4.26	3.24 to 5.60
3b	7.06	5.03 to 9.90

Abbreviation: HR: hazard ratio; mLNR: metastatic lymph node ratio; mLNS: metastatic lymph node stage.