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. 2017 Apr 24;8(28):45725–45735. doi: 10.18632/oncotarget.17392

Figure 5. ERBB4 is a direct target of miR-551b.

Figure 5

(A) Sequence alignment of miR-551b with the 3′ UTR of ERBB4 and the mutated miR-551b binding site are shown. (B) The mRNA expression of ERBB4 in normal and tumor tissues is shown. (C) Survival curve of GC patients from the TCGA database showing the relationship between expression of ERBB4 and patient survival time. (D-G) Dual luciferase reporter assay comparing control amd miR-551b mimic treated MNK45 and SGC7901 cells in presence of wild type or mutated ERBB4 UTR is shown. **, p < 0.01.