Figure 8. Xenograft mouse model shows that miR-551b mimics significantly inhibit tumor growth and extend life span.

(A and B) Live imaging of subcutaneous and peritoneal tumor growth at 14 days in untreated (left) and miR-551b mimic treated GC cells (right) demonstrating that miR-551b diminishes tumor growth in nude mice. (C) Tumor volume curve showing growth of untreated and miR-551b mimic transfected GC cell tumors over a period of time (5 weeks). (D) Comparison of survival curves of nude mice injected with GC cells that are either untreated (blue) or transfected miR-551b mimic (red) are shown.