Table 8. Univariate and multivariate analyses of clinicopathological variables associated with EGFR-sensitive mutations.

Variable	Hazard ratioa	95.0% CI	p-value
Univariate analysis
Age	−0.25	−4.05-3.13	0.811
Sex (male vs. female)	1.60	N/A	0.236
Complications (no vs. yes)	0.67	N/A	0.478
Smoker (no vs. yes)	10.58	N/A	0.002*
miR-107	2.15	0.49–11.34	0.033*
miR-122	1.58	−0.60–5.40	0.116
miR-195	−2.36	−7.41–-0.66	0.019*
Multivariate analysis
Age	2.03	0.93–1.01	0.154
Sex (male vs. female)	1.08	0.63–4.62	0.299
Complications (no vs. yes)	2.55	0.86–4.53	0.110
Smoker (no vs. yes)	9.44	1.85–16.25	0.002*
miR-107	4.08	0.78–1.00	0.043*
miR-122	0.69	0.79–1.10	0.405
miR-195	2.81	0.99–1.07	0.094
Further multivariate analysis
Smoker (no vs. yes)	9.90	1.55–6.67	0.002*
miR-107	5.56	0.78–0.98	0.018*

* p < 0.05

^aChi-square values for categorical variables and t-test values for continuous variables in the univariate analysis and Wald values for variables in the multivariate analysis

Abbreviations: N/A, not applicable