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. 2017 Apr 26;8(28):45874–45887. doi: 10.18632/oncotarget.17437

Figure 6. Combination treatment induced cell apoptosis by reducing miR-200c expression.

Figure 6

(A) Expression of miR-200c in RPC, GH3 and MMQ cells (p = 0.003). (B) qRT-PCR demonstrated that combination treatment specifically reduced miR-200c expression in GH3 (p = 0.013) and MMQ (p = 0.027) cells. (C) qRT-PCR was used to detect the transfection efficiency in GH3 and MMQ cells. MI indicates transfection with the miR-200c analog, IN indicates transfection with the miR-200c inhibitor, and Vector indicates the negative control. (D) Caspase-3 activity assay in transfected cells after combination treatment. (E) FACS was used to estimate apoptosis in transfected cells after combination treatment. Experiments were repeated at least three times; p < 0.05 versus control.