Table 1B. KRAS exon 2 population (N=36).
KRAS wt | KRAS mut | KRAS wt | KRAS mut | |||||
---|---|---|---|---|---|---|---|---|
pp70S6K1T389 ≤ median | pp70S6K1T389 > median | pp70S6K1T389 ≤ median | pp70S6K1T389 > median | pAKTS473 low | pAKTS473 high | pAKTS473 low | pAKTS473 high | |
pERK1/2T202/Y204≤ median | 7 | 3 | 9 | 0 | 8 | 2 | 5 | 4 |
pERK1/2T202/Y204> median | 2 | 10 | 1 | 4 | 4 | 8 | 0 | 5 |
p = 0.011, chi-square;odds ratio (95% CI): 11.667 (1.527-89.121) | p = 0.001, chi-square;odds ratio (95% CI): 5.000 (0.866-28.861)1 | p = 0.029, chi-square; odds ratio (95% CI): 8.000 (1.127-56.793) | p = 0.038, chi-square;odds ratio (95% CI): 0.444 (0.214-0.923)2 |
1For pp70S6K1T389 ≤ median cohort; 2for pAKTS473 high cohort.