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. 2017 Apr 26;8(28):45898–45917. doi: 10.18632/oncotarget.17438

Table 2B. RAS, BRAF, PIK3CA and marker correlation.

pAKTS473 pERK1/2T202/Y204 pp70S6K1T389 PTENloss
All RAS mutation1
 p-value* 0.340 0.035# 0.175 0.168
BRAF mutation2
 p-value* 0.406 0.161 0.219 0.275
all RAS or BRAF mutation1,2
 p-value* 0.392 0.111 0.097§ 0.109
PIK3CA mutation3
 p-value* 0.001* 0.055§ 0.496 0.214

n.a.: not applicable; 1KRAS exon 2-4, NRAS exon 2-4; 2BRAF exon 15; 3PIK3CA exon 10 and 21; *Spearman-Rho; #denotes significance (p < 0.05); §trend (p < 0.1).