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. 2017 May 2;8(28):46090–46103. doi: 10.18632/oncotarget.17552

Figure 6. HOXA-AS2 controls the expression of the targets of miR-520c-3p.

Figure 6

(A) The OncomiRDB database supplied the direct targets (TGFBR2 and RELA) of miR-520c-3p. (B) The OncomiRDB regulatory network showed the regulatory relationships of miR-520c-3p, TGFBR2 and RELA. (C, D) qRT-PCR analysis of miR-520c-3p expression in MCF-7 and MDA-MB-453 cells transfected with control plus scramble, control plus miR-520c-3p, and HOXA-AS2 plus miR-520c-3p (*P < 0.05). (E-H) qRT-PCR (up panel) and Western blot (down panel) analysis of TGFBR2 and RELA expression in breast cancer cells treated with various vectors (*P < 0.05).