Skip to main content
. 2017 May 2;8(28):46121–46135. doi: 10.18632/oncotarget.17555

Figure 5. The regulation of cell migration by the MNKs does not require NDRG1.

Figure 5

NDRG1 was knocked down by an siRNA in MDA-MB-231 cells and cells were treated with 5 μM MNK-I1. A scrambled siRNA (siScr) was used as a negative control. (A) Cell lysates were analysed by Western blot. Wound healing was tested in MDA-MB-231 cells in the presence of MNK-I1 (5 μM) where indicated. (B) Photographs were taken under a light microscope and (C) quantified using ImageJ. (D) A cell invasion assay was performed to measure the invasive ability of these cells. Data are shown as mean ± S.E.M. from three replicates. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.