Table 2. The gene list for the differentially expressed genes of cervical cancer (CxCa-DEGs) and the cervical cancer signature (CxCa-Sig).
CxCa-DEGs | CxCa-Sig | |
---|---|---|
Upregulated genes | AURKA, BIRC5, BUB1, CDC20, CDC45, CDK1, CDKN2A, CENPA, CKS1B, CKS2, DNMT1, GINS2, HLTF, KIF11, KIF23, KIF2C, MCM5, MCM6, NDC80, NEK2, NUSAP1, PLAU, POLE2, PRC1, RAD51AP1, RFC4, RFC5, SMC4, STMN1, SYCP2, TACC3, TIMELESS, TK1, TOP2A, TOPBP1, TPX2, TTK, TYMS (38 genes) | AURKA, BIRC5, BUB1, CDC20, CDC45, CDK1, CDKN2A, CENPA, CKS1B, CKS2, GINS2, KIF11, KIF23, KIF2C, MCM5, MCM6, NDC80, NEK2, POLE2, PRC1, RFC4, RFC5, SMC4, STMN1, TACC3, TIMELESS, TK1, TOP2A, TOPBP1, TPX2, TTK, TYMS (32 genes) |
Downregulated genes | CDA, CFD, CRNN, EDN3, ENDOU, GSTA4, LDOC1, PDGFD, PPP1R3C, UPK1A (10 genes) | CDA (1 gene) |
CxCa-DEGs represented the overlapped DEGs from 7 microarray data sets. The network of CxCa-DEGs was reconstructed by the STRING database. The genes directly linked to each other were used as a CxCa-Sig for further analyses.