Table 3. Mean quality of life scores of 2D-CRT versus IMRT without concurrent chemotherapy.
| Scales | 2D-CRT (n=33) | IMRT (n=22) | t | p | ||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| EORTC QLQ-C30 | ||||||
| Global quality of life | 69.95 | 15.30 | 86.74 | 11.69 | −4.364 | 0.000 |
| Physical functioning | 80.61 | 19.10 | 97.58 | 8.11 | −4.528 | 0.000 |
| Role functioning | 80.81 | 20.46 | 98.48 | 4.90 | −4.761 | 0.000 |
| Emotional functioning | 74.49 | 23.75 | 95.08 | 14.47 | −3.990 | 0.000 |
| Cognitive functioning | 66.67 | 30.33 | 94.70 | 9.47 | −4.959 | 0.000 |
| Social functioning | 66.67 | 24.65 | 96.97 | 6.58 | −6.712 | 0.000 |
| Fatigue | 26.94 | 19.84 | 6.06 | 8.21 | 5.391 | 0.000 |
| Nausea/emesis | 4.04 | 9.35 | 1.52 | 4.90 | 1.306 | 0.197 |
| Pain | 13.64 | 17.90 | 5.30 | 7.95 | 2.350 | 0.023 |
| Dyspnea | 9.09 | 15.08 | 1.52 | 7.11 | 2.500 | 0.016 |
| Insomnia | 28.28 | 20.62 | 12.12 | 21.93 | 2.777 | 0.008 |
| Appetite loss | 14.14 | 18.69 | 0.00 | 0.00 | 4.346 | 0.000 |
| Constipation | 8.08 | 20.46 | 0.00 | 0.00 | 2.268 | 0.030 |
| Diarrhea | 7.07 | 18.18 | 1.52 | 7.11 | 1.584 | 0.120 |
| Financial problems | 39.39 | 28.20 | 9.09 | 15.19 | 5.152 | 0.000 |
| EORTC QLQ-H&N35 | ||||||
| Pain | 10.86 | 14.05 | 1.52 | 4.18 | 3.590 | 0.001 |
| Swallowing | 22.22 | 18.00 | 1.89 | 5.10 | 6.129 | 0.000 |
| Senses | 23.74 | 17.69 | 6.06 | 8.21 | 4.990 | 0.000 |
| Speech | 9.43 | 11.82 | 1.52 | 3.90 | 3.564 | 0.001 |
| Social contact | 24.24 | 22.57 | .38 | 1.78 | 6.046 | 0.000 |
| Social eating | 12.12 | 11.72 | .30 | 1.42 | 5.730 | 0.000 |
| Sexuality | 47.47 | 30.08 | 11.36 | 20.82 | 5.260 | 0.000 |
| Teeth | 40.40 | 32.01 | 9.09 | 18.35 | 4.599 | 0.000 |
| Opening mouth | 27.27 | 25.62 | 1.52 | 7.11 | 5.468 | 0.000 |
| Dry mouth | 54.55 | 23.30 | 16.67 | 19.92 | 6.249 | 0.000 |
| Sticky saliva | 7.07 | 16.15 | 1.52 | 7.11 | 1.739 | 0.089 |
| Coughing | 10.10 | 17.65 | 10.61 | 18.93 | −0.101 | 0.920 |
| Feeling ill | 18.18 | 20.57 | 6.06 | 16.70 | 2.400 | 0.020 |
| Pain killers | 3.03 | 9.73 | 0.00 | 0.00 | 1.789 | 0.083 |
| Nutritional supplements | 21.21 | 20.10 | 6.06 | 13.16 | 3.378 | 0.001 |
| Feeding tube | 0.00 | 0.00 | 0.00 | 0.00 | 0.000 | 1.000 |
| Weight loss | 2.02 | 8.08 | 1.52 | 7.11 | 0.238 | 0.813 |
| Weight gain | 1.01 | 5.80 | 0.00 | 0.00 | 0.814 | 0.419 |
2D-CRT: two-dimensional conventional radiotherapy; IMRT: intensity-modulated radiotherapy; SD: standard deviation; EORTC QOL-C30: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30; EORTC QOL-H&N35: The EOTRC Quality of Life Questionnaire-Head and Neck 35.