Table 4. Mean quality of life scores of 2D-CRT versus IMRT with concurrent chemotherapy.
| Scales | 2D-CRT (n=14) | IMRT (n=37) | t | p | ||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| EORTC QLQ-C30 | ||||||
| Global quality of life | 53.57 | 11.65 | 73.2 | 15.48 | −4.294 | 0.000 |
| Physical functioning | 64.29 | 14.93 | 86.31 | 13.96 | −4.933 | 0.000 |
| Role functioning | 59.52 | 19.3 | 83.33 | 15.21 | −4.628 | 0.000 |
| Emotional functioning | 50.6 | 26.65 | 79.95 | 18.37 | −4.48 | 0.000 |
| Cognitive functioning | 47.62 | 22.51 | 77.48 | 15.82 | −5.334 | 0.000 |
| Social functioning | 48.81 | 19.02 | 82.43 | 16.17 | −6.313 | 0.000 |
| Fatigue | 51.59 | 17.76 | 20.12 | 19.92 | 5.178 | 0.000 |
| Nausea/emesis | 4.76 | 7.81 | 1.35 | 6.06 | 1.474 | 0.157 |
| Pain | 28.57 | 10.19 | 10.36 | 13.24 | 4.643 | 0.000 |
| Dyspnea | 16.67 | 17.3 | 6.31 | 18.98 | 1.78 | 0.081 |
| Insomnia | 61.9 | 22.1 | 24.32 | 23.11 | 5.243 | 0.000 |
| Appetite loss | 19.05 | 17.12 | 2.7 | 12.12 | 3.276 | 0.004 |
| Constipation | 4.76 | 12.1 | 4.5 | 19.5 | 0.046 | 0.964 |
| Diarrhea | 14.29 | 17.12 | 2.7 | 9.22 | 2.403 | 0.029 |
| Financial problems | 57.14 | 20.37 | 35.14 | 27.16 | 2.747 | 0.008 |
| EORTC QLQ-H&N35 | ||||||
| Pain | 13.1 | 7.1 | 6.31 | 6.92 | 3.106 | 0.003 |
| Swallowing | 33.93 | 14.05 | 11.26 | 10.25 | 6.349 | 0.000 |
| Senses | 28.57 | 17.82 | 13.06 | 15.28 | 3.09 | 0.003 |
| Speech | 13.49 | 10.83 | 3 | 7.7 | 3.319 | 0.004 |
| Social contact | 39.88 | 18.83 | 11.94 | 13.26 | 5.096 | 0.000 |
| Social eating | 14.29 | 13.3 | 3.78 | 7.46 | 2.794 | 0.013 |
| Sexuality | 72.62 | 30.39 | 32.43 | 21.14 | 5.35 | 0.000 |
| Teeth | 54.76 | 21.11 | 23.42 | 22.03 | 4.583 | 0.000 |
| Opening mouth | 33.33 | 18.49 | 15.32 | 21.65 | 2.959 | 0.006 |
| Dry mouth | 66.67 | 18.49 | 28.83 | 25.05 | 5.135 | 0.000 |
| Sticky saliva | 16.67 | 21.68 | 4.5 | 17.85 | 1.872 | 0.076 |
| Coughing | 21.43 | 16.57 | 9.91 | 15.45 | 2.33 | 0.024 |
| Feeling ill | 33.33 | 18.49 | 9.01 | 16.94 | 4.464 | 0.000 |
| Pain killers | 2.38 | 8.91 | 3.6 | 10.49 | −0.386 | 0.701 |
| Nutritional supplements | 28.57 | 12.1 | 16.22 | 16.89 | 2.898 | 0.007 |
| Feeding tube | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 1 |
| Weight loss | 14.29 | 17.12 | 0.9 | 5.48 | 2.87 | 0.012 |
| Weight gain | 4.76 | 12.1 | 14.41 | 16.74 | −2.273 | 0.03 |
2D-CRT: two-dimensional conventional radiotherapy; IMRT: intensity-modulated radiotherapy; SD: standard deviation; EORTC QOL-C30: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30; EORTC QOL-H&N35: The EOTRC Quality of Life Questionnaire-Head and Neck 35.